A systematic review to examine the relationship between objective and patient‐reported outcome measures in sinonasal disorders: recommendations for use in research and clinical practice

Background Common sinonasal disorders include chronic rhinosinusitis (CRS), allergic rhinitis (AR), and a deviated nasal septum (DNS), which often coexist with shared common symptoms including obstruction, olfactory dysfunction, rhinorrhea. Various objective outcome measures patient-reported (PROMs) are used to assess disease severity; however, there is limited evidence in the literature on correlation between them. This systematic review aims examine relationship them provide recommendations. Methods A search of MEDLINE EMBASE identified studies quantifying correlations PROMs for conditions using narrative synthesis. Results In total, 59 met inclusion criteria. For rhinomanometry shows lack whereas peak inspiratory flow (PNIF) strongest (r > 0.5). The Sniffin’ Stick test stronger 0.5) than University Pennsylvania Smell Identification Test (UPSIT) < Computed tomography (CT) sinus scores show little endoscopic ratings (weak correlation, r Conclusion Overall, assessing poorly correlated, we recommend that be validated depending setting. PNIF should routine clinical practice obstruction; acoustic rhinometry may useful research. Sticks recommended dysfunction UPSIT as an alternative. CT excluded CRS measure, combination until further research conducted.